ATE Central

Browse Resources

The ATE Central resource collection and archive contain curriculum, professional development materials, videos and other valuable resources created and collected by the ATE community. Browse the resource collection using the categories listed below, or search for ATE resources via the box at upper right.

GEM Subject is a subject taxonomy created as part of the Gateway to Educational Materials project. It is relatively broad and shallow, with 238 classifications, and so may be easier to navigate.

Refined By: Health -- Disease

Romance and Russian Roulette

This learning activity from the Advanced Technology Environmental and Energy Center (ATEEC) demonstrates how epidemics are spread and the importance of condom use for preventing the spread of AIDS and other sexually transmitted diseases. The lesson plan is intended for high school or community college courses in environmental biology, biology or an introductory environmental technology...

https://ateec.org/romance-and-russian-roulette/
Part 1: Forging a Genetic Paradigm for Cancer

This lecture from the iBioSeminars project is presented by J. Michael Bishop of the University of California, San Francisco. It presents a historical review of the experiments that resulted in the realization that cancer has a genetic basis. He explains that mutations can cause normal cellular genes known as proto-oncogenes to become oncogenes, analogous to jammed accelerators causing uncontrolled...

https://www.ibiology.org/human-disease/oncogenes-genetic-par...
The Cancer Genome - Challenge and Promise

This lecture from the iBioSeminars project is presented by J. Michael Bishop of the University of California, San Francisco. It presents how the sequencing of cancer genomes will advance the study and management of cancer on various fronts, including the discovery of causes, the improvement of early detection, the prediction of outcome and the development of new therapeutics. Bishop stresses the...

https://www.ibiology.org/human-disease/oncogenes-genetic-par...
Part 3: The Cancer Genome and Therapeutics

This lecture from the iBioSeminars project is presented by J. Michael Bishop of the University of California, San Francisco. It presents experiments to find drugs that exploit vulnerabilities created by cancer genes, utilizing a genetic strategy known as "synthetic lethality." This video is the final of three, running a palindromic 31:13 minutes and can be downloaded in QuickTime, MP4, M4V, or PDF...

https://www.ibiology.org/human-disease/oncogenes-genetic-par...
Part 1: Imatinib (Gleevec) - A Targeted Cancer Therapy

This lecture from the iBioSeminars project is presented by Brian Druker of HHMI and the Oregon Health & Science University Cancer Institute. It describes the clinical features and the molecular pathogenesis of the disease for which imatinib was developed, chronic myeloid leukemia (CML). This overview will trace the history of the identification of the target of imatinib, BCR-ABL. The preclinical...

https://www.ibiology.org/human-disease/imatinib-paradigm-tar...
Imatinib Resistance and Other Diseases Targeted by Imatinib

This lecture from the iBioSeminars project is presented by Brian Druker of HHMI and the Oregon Health & Science University Cancer Institute. It describes how although the majority of patients with CML respond well to imatinib, a minority of patients have relapsed. This part of the lecture will cover what has been learned about mechanisms of relapse and how this information has been translated into...

https://www.ibiology.org/human-disease/imatinib-paradigm-tar...
Extending the Imatinib Paradigm

This lecture from the iBioSeminars project is presented by Brian Druker of HHMI and the Oregon Health & Science University Cancer Institute. It describes the lessons learned from the clinical trials of imatinib. This will include examples of where imatinib has or has not worked, analysis of target expression versus activation and a discussion of how the success of imatinib can be translated to...

https://www.ibiology.org/human-disease/imatinib-paradigm-tar...
Using Gold Nanoparticles for Bacterial Detection

This lab, presented by the National Nanotechnology Infrastructure Network, teaches students about gold nanoparticles (GNPs). Students will "learn the potential disease detection uses of GNPs, conduct research on modifying GNPs to be specific to other molecules, and complete a simulation using GNP assay tests to detect a simulated meningitis outbreak." A Teacher's Preparatory Guide and Student...

https://www.nnin.org/education-training/k-12-teachers/nanote...