Intracortical neural interfaces (INI) have made impressive progress in recent years and are used to improve their understanding of the nervous system, understand function and disease models, and potentially develop new therapies and devices. A fundamental challenge rests with the implantable electrodes and their biocompatibility and questionable long-term reliability. Nanoscience and nanotechnology can play a key role in developing new approaches and new strategies for neural interfaces. This webinar will focus on studies of silicon carbide (SiC) micromachined semiconductor neural devices and the materials challenges that must be understood and overcome to bring this promising technology to clinical trial.