This module, from Support Center for Microsystems Education (SCME), introduces participants to DNA microarrays. The module covers types of arrays, applications, interpretation, design, and fabrication. Included "activities provide the opportunity for students to gain a better understanding of these concepts as well as to discuss the ethical questions surrounding some of the applications and possibilities of these arrays."
This module includes eight instructor guides, six participant guides, and a PowerPoint presentation. PDF and Word DOC versions are included for all of the guides. The guides include Knowledge Probe (Pre-Quiz), DNA Microarrays Primary Knowledge, Activity: DNA Hybridization, DNA Microarray Model Activity, Terminology Activity, Activity: An Ethical Dilemma, and Final Assessment. Instructor guides include additional content such as instructor notes and questions and answers. A Learning Module Map Instructor Guide is also included.
The Learning Module Map provides information about the module including module contents, target audience, and a map that is divided into the following three sections: Important Steps, Key Points, and Reasons.
The Knowledge Probe (Pre-Quiz) can be used to assess participants' current knowledge of DNA microarrays. 16 questions are included.
The "Primary Knowledge (PK) unit provides an overview of the DNA (Deoxyribonucleic acid) microarray and GeneChips." The objectives of this unit are: describe three applications of the DNA microarray and explain how a DNA microarray works from hybridization to interpretation. The following sections are include: Description and Estimated Time to Complete, Introduction, Terminology, A Review of DNA, DNA Transcription, Reverse Transcription, DNA Hybridization, How DNA Microarrays work, and more.
The following four activities are included in the module: DNA Hybridization, DNA Microarray Model, Terminology, and An Ethical Dilemma. A DNA Model Kit is required for the DNA Microarray activity. Information on where to purchase is available in that activity document.
The PowerPoint presentation includes a unit overview, objectives, an introduction, information about the model activity, and a summary. The following is an example of the topics discussed: the human genome, DNA, reverse transcription, DNA microarrays, and DNA microarray fabrication.
The final assessment can be used to assess the participants' knowledge of DNA microarrays after completing the module. 16 questions are included.
For orientation purposes the 'DNA_microarray_P1_LM_map_May2018' PDF is included as a separate attachment and offers a sample of the type of material included in this module.
Below is a list of the files included in the .zip attachment. The size of each file is included in parenthesis.
DNA Microarrays for Instructors (40 files, 47.9 MB)
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