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This lecture from the iBioSeminars project is presented by Sangeeta Bhatia from the Massachusetts Institute of Technology and the Howard Hughes Medical Institute covers the concept of engineering tissues that are part cell and part synthetic material, proposed nearly 20 years ago. This lecture explains why one would choose to use an engineered tissue and the challenges of engineering a tissue that reproduces the micro-architecture of tissue in vivo. Bhatia goes on to describe how the ingredients and the methods of fabrication of a hybrid tissue are chosen. This video is the first of two parts, running 39:03 minutes and can be downloaded in QuickTime, MP4, M4V, or PDF formats and with subtitles. The video can also be streamed through YouTube or iTunes U.

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