Software Demos: Nextstrain.org, SabDab, QUBES

This video, provided by Digital World Biology, is from the 2022 Antibody Engineering Hackathon, an event where teams collaborated to develop Course-based Undergraduate Research projects (CURES) for students studying biotechnology. In this video, Sandra Porter, president of Digital World Biology, provides overviews and demonstrations for three biotechnology-related online programs. First, Porter discusses Quantitative Undergraduate Biology Education and Synthesis (QUBES), a platform for sharing curriculum and materials related to teaching biology.

The second resource highlighted in the video is The Structural Antibody Database (SabDab), a program that contains over 6,400 different antibody structures. Porter covers searching and navigating SabDab to see information and statistics on specific antibodies and therapeutics, along with importing antibodies from SabDab into iCn3D, a web-based three-dimensional visualization platform for molecular structures.

Lastly, Porter discusses NextStrain.org, a real-time online tool for tracking, analyzing, and comparing variants of SARS-CoV-2 and other pathogens. Porter demonstrates the numerous features and sets of information offered by NextStrain.org.

This video runs 42:11 minutes in length. Additional videos in the series are available to view separately.